15 years of zebrafish chemical screening

Zebrafish heart regeneration: 15 years of discoveries

Cardiovascular disease is the leading cause of death worldwide. Compared to other organs such as the liver, the adult human heart lacks the capacity to regenerate on a macroscopic scale after injury. As a result, myocardial infarctions are responsible for approximately half of all cardiovascular related deaths. In contrast, the zebrafish heart regenerates efficiently upon injury through robust ...

15 Years of Rolland

The paper presents 15 years of research conducted on the Bremen Autonomous Wheelchair “Rolland”. Rolland is a mobility assistant for the handicapped and the elderly. The paper presents the different versions of Rolland that were built over the years, as well as the special input devices that are used with Rolland. Contributions were made to the state of the art in the areas of self-localization...

Designing zebrafish chemical screens.

The zebrafish is proving to be highly amenable to in vivo small molecule screening. With a growing number of screens successfully completed, a rich interface is being created between disciplines that have historically used zebrafish (e.g., embryology and genetics) and disciplines focused on small molecules (e.g., chemistry and pharmacology). Navigating this interface requires consideration of t...

Implications of family protective-risk index for screening cognitive development of children aged 13-15 years.

BACKGROUND A simple screening tool is essential for priority setting and operating activities in communities. OBJECTIVE The present study aimed to identify the implications of a family protective-risk index (FPRI) for screening cognitive development of children aged 13-15 years. MATERIAL AND METHOD The cross-sectional survey among 319 children aged 13-15 years old was conducted in one distr...

Congenital hypothyroidism: optimal management in the light of 15 years' experience of screening.